Advanced Breast Cancer: Better Sleep Predicts Longer Survival

woman sleeping serenely

What You Need to Know: Sleep efficiency, a ratio of time asleep to time spent in bed, is predictive of survival time for women with advanced breast cancer. This is the first study to demonstrate the long-term detrimental effects of objectively quantified sleep on survival in women with advanced cancer.

Among the women diagnosed with advanced breast cancer, those who sleep efficiently – not necessarily for longer period – are likely to live longer than those who do not get quality sleep, a study indicated. Sleep efficiency refers to the ratio of time asleep to time spent in bed.

“Good sleep seems to have a strongly protective effect, even with advanced breast cancer,” said Oxana Palesh, an assistant professor at Stanford University. “We were surprised by the magnitude of the relationship between sleep quality and overall survival even after we accounted for medical and psychological variables that typically predict survival.”

There is no association between sleep duration and survival, the findings of the research showed.

Details, details: The study involved 97 women with advanced breast cancer who had a mean age of 55 years. Objective sleep parameters were measured by wrist actigraphy for three consecutive days. Higher sleep efficiency was significantly associated with lower mortality over the ensuing six years. Mean survival was 68.9 months for efficient sleepers compared with 33.2 months for participants with poor sleep efficiency. A 10 percent increase in sleep efficiency reduced the estimated hazard of subsequent mortality by 32 percent, further analysis showed.

My Take: Sleep disruption may lead to diminished immune function or impaired hormonal stress responses that are more directly responsible for the decrease in survival. This study is in the journal Sleep. I’m Dr. Michael Hunter.

Reference: http://www.business-standard.com/article/news-ians/better-sleep-ups-survival-period-of-breast-cancer-patients-114050300722_1.html

The small print: The material presented herein is informational only, and is not designed to provide specific guidance for an individual. Please check with a valued health care provider with any questions or concerns. As for me, I am a Harvard- , Yale- and UPenn-educated radiation oncologist, and I practice in the Seattle, WA (USA) area. I feel genuinely privileged to be able to share with you. If you enjoyed today’s offering, please consider clicking the follow button at the bottom of this page.

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understandcancerin60minutes

Harvard AB Yale MD UPenn Radiation Oncology Radiation Oncologist, Seattle area

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